Table 3

Effect of appendicectomy on ulcerative colitis characteristics (n=307)

Appendicectomy
PhenotypenYes (n=21)No (n=286)OR (95%CI)p Value
S, subtotal colitis; T, total colitis; L, colitis distal to splenic flexure; P, ulcerative proctitis.
*Six patients excluded with colectomy for high grade dysplasia or colorectal carcinoma.
†Five patients excluded with colectomy for high grade dysplasia or colorectal carcinoma.
Mean (SEM) age at diagnosis (y)37.8 (2.8) 31.3 (1.0)0.08
Colectomy*
    No24120 (100%)221 (78.6%)
    Yes60 0 (0%) 60 (21.4%)0.02
Immunosuppression
    No23520 (95.2%)215 (75.2%)1.00 (referent)
    Yes72 1 (4.8%) 71 (24.8%)0.15 (0.02–1.15)0.04
Colectomy or immunosuppression†
    No19520 (95.2%)175 (62.3%)1.00 (referent)
    Yes107 1 (4.8%)106 (37.7%)0.09 (0.01–0.66)0.003
Distribution
    L&P173 8 (38.1%)165 (57.9%)1.00 (referent)
    S&T13313 (61.9%)120 (42.1%)2.23 (0.9–5.56)0.08
Duration between appendicectomy and UC (y)
    S&T (mean (SEM))1315.5 (3.4)
    L&P (mean (SEM))810.3 (2.7)
    Overall (mean (SEM))2113.5 (2.4)0.30