Clinical and biochemical data of patients with cirrhosis and controls
| Cirrhosis group | Control group | |
|---|---|---|
| Values are mean (SEM). | ||
| †Reference interval in parentheses. | ||
| Significant difference compared with controls: *p<0.02. | ||
| Age (y) | 50.5 (1.3) | 54.1 (3.4) |
| Sex (M/F) | 35/16 | 6/7 |
| Body height (cm) | 172 (1.3) | 167 (2.5) |
| Body weight (kg) | 70.0 (2.3) | 61.5 (4.8) |
| Body mass index (kg/m2) | 23.6 (0.7) | 22.0 (1.6) |
| Ascites (+/−) | 21/30 | |
| Diuretics (no/yes) | 23/28 | |
| Serum albumin (µmol/l; 540–800)† | 480 (12) | 527 (16) |
| Serum alanine aminotransferase (U/l; 10–40) | 78 (29)* | 21 (1.5) |
| Serum bilirubin (µmol/l; 2–17) | 40 (11)* | 7.0 (0.7) |
| Serum alkaline phosphatase (U/l; 50–275) | 358 (28)* | 169 (25) |
| Coagulation factors 2, 7, 10 (index; 0.70–1.30) | 0.60 (0.04)* | 1.04 (0.05) |
| Galactose elimination capacity (mmol/min; M>1.70, F>1.40) | 1.59 (0.07) | — |
| Indocyanine green clearance (ml/min; 300–700) | 247 (23)* | 469 (40) |
| Serum Na (mmol/l; 136–146) | 135 (1) | 139 (1) |
| Serum K (mmol/l; 3.5–5.0) | 4.0 (0.1) | 4.3 (0.1) |
| Serum creatinine (µmol/l; 40–110) | 79 (7) | 80 (6) |
| Haemoglobin (mmol/l; 7.5–10.9) | 7.4 (0.2) | 7.8 (0.3) |