Table 4

Arterial and cubital venous pro-brain natriuretic peptide (proBNP) and brain natriuretic peptide (BNP) concentrations in patients with cirrhosis

Cirrhosis, Child group (33–69 y)
A (n = 15)B (n = 23)C (n = 13)Controls (34–73 y) (n = 13)Healthy subjects (23–65 y) (n = 90)
Significant differences: *from healthy subjects (p<0.002), afrom Child class A (p<0.05), bfrom controls (p<0.05), cfrom cirrhosis (p<0.02).
ProBNP (artery) (pmol/l)
    Mean9.620.8a b24.5a b13.2c
    SEM2.23.44.52.9
    Median9.018.020.012.5
    Range(0.0–35.7)(1.0–57.3)(1.0–66.0)(0.71–26)
ProBNP (cubital vein) (pmol/l)
    Mean10.0*20.7* a23.9*a14.2*c2.2
    SEM1.74.85.72.60.4
    Median10.017.019.013.5
    Range(0.0–22)(20–62)(1.0–58)(1.0–27)(0–16)
BNP (artery) (pmol/l)
    Mean5.914.3a b14.3a b7.9c
    SEM1.32.43.01.7
    Median5.312.412.15.8
    Range(0.8–15.2)(1.3–39.3)(3.1–38.5)(0.5–16.9)
BNP (cubital vein) (pmol/l)
    Mean5.913.6*a b14.7* a b4.7c1.7
    SEM1.22.23.51.50.1
    Median5.314.413.34.9
    Range(1.4–14.4)(2.0–29.9)(2.3–41.9)(0.6–13.9)(0–5.3)
Ratio
    ProBNP/BNP
        Mean1.811.601.972.28
        SEM0.240.180.280.39