Percentage of T cells with monoclonal T cell receptor γ (TCR-γ) gene rearrangements in patients with refractory coeliac sprue (RCS) and two groups of patients with coeliac disease (CD) (active coeliac disease (ACD) and coeliac disease on a gluten free diet (GFD-CD)) in gastric, colonic, and blood samples
Blood | Stomach | Colon | Duodenum | Jejunum | |
---|---|---|---|---|---|
Percentages correspond to the number of patients with monoclonality/number of patients tested. | |||||
p values for comparisons between *RCS and ACD, and †RCS and GFD-CD. | |||||
ACD | 1/16 (1%) | 0/4 (0%) | 0/18 (0%) | 0/11 (0%) | |
GFD-CD | 1/9 (11%) | 0/3 (0%) | 0/10 (0%) | 0/4 (0%) | |
RCS | 4/9 (44%) | 8/13 (62%) | 8/10 (64%) | 15/15 (100%) | 10/10 (100%) |
p* | <0.01 | <0.05 | <0.001 | <0.001 | |
p† | <0.05 | <0.05 | <0.001 | <0.001 |