Table 1

Quantitative bacteriology of caecal content by bacterial cultures

TreatmentDirect microscopic bacterial counts (×108)Total aerobes (×107)E coli (×107)Enterococci (×107)Total anaerobes (×108)Bacteroides spp (×107)
Direct microscopic bacterial counts and caecal concentrations of aerobic bacteria, Escherichia coli, enterococci, as well as total anaerobic bacteria, including Bacteroides spp, in gnotobiotic IL-10−/− mice colonised with specific pathogen free flora and treated with ciprofloxacin (Cipro), metronidazole (MNZ), or vancomycin-imipenem (V+I). Values are given as mean (SEM) colony forming units (CFU) per gram caecal contents.
*p<0.05, **p<0.01 versus water controls.
Water38 (12)5 (2)7 (3)48 (20)86 (30)32 (8)
MNZ43 (7)20 (10)84 (13)**57 (30)4.8 (5)*<0.001**
Cipro24 (6)<0.001**<0.001**0.2 (0.1)**96 (50)28 (5)
V+I1 (0.1)**21 (10)<0.001**<0.001**<0.001**<0.001**