Table 1

Phenotype of liver dendritic cells

Species	Maturation status	Markers	Comments (ref)
DC, dendritic cell; GM-CSF, granulocyte macrophage-colony stimulating factor; IL, interleukin; MHC, major histocompatibility complex.
Mouse	Immature	CD11c⁺CD40^loCD80^loCD86^loMHC II^lo	2 subsets:^1,^14,^41,¹⁰¹
		(1) CD8α^-CD11b⁺	(1) Myeloid related^12,¹⁰²
		(2) CD8α⁺CD11b⁻	(2) Lymphoid related
		B220^-CD11c⁺CD205^-F4/80^-	Yoneyama⁶⁵
		CD205⁺OX2⁺	Gorczynski,³⁷Drakes,⁴³Gorczynski ¹⁰³
		CD11b⁺CD24⁺CD44⁺CD45⁺CD11c^loCD16/3 2^loCD40^lo CD80^lo CD86^loCD205^loF4/80^lo	Generated from liver progenitor cells with GM-CSF; called liver derived DC progenitors.^32,³³
	Mature	CD11c⁺MHC II^hiCD86^hi
		CD11c⁺CD54⁺CD205⁺MHC II⁺CD11b^modCD86^modCD11a/CD18^mod B220^-CD3ε⁻Gr1⁻	Yoneyama⁶⁵
	Other	CD205^hi B220⁺CD11c⁻ CD19⁻	Generated from liver progenitor cells with IL-3 and CD40L. Ig gene rearrangement occurs but no surface expression. Activate then subsequently induce apoptosis of T cells.³⁴
Rat	Immature	MHC II⁺ANAE⁻FcR⁻	ANAE=α-naphtylacetate esterase=a non-specific esterase; FcR=Fc receptor⁵³
	Mature	MHC I^hiMHC II^hiCD54⁺OX62⁺	Brenan,³⁶Matsuno,⁵⁶Saiki⁹²
		(1) ED1⁺ED2^-OX6⁺, (2) ED1⁻ED2⁻OX6⁺	2 subsets of OX62⁺ cells¹⁰⁴
		MHC II⁺CD54⁺OX62⁺CD90⁺CTLA-4 Counter-receptor⁺	Chen-Woan³⁵
		CD4⁺	Variable expression is common in MHC II⁺ DC and peripheral tissues of rat⁵¹¹⁰⁵
Human	Immature	CD11a⁺ CD45⁺MHC II⁺	Prickett⁷
		CD83^loCD86^loMHC II^lo	Ninomiya ⁸⁴
	Mature	CD200⁺	Goddard¹⁰⁶
		CD83⁺CD86⁺	Goddard¹⁰⁷