Table 2

Cumulative hepatitis B e antigen (HBeAg) seroconversion rates in patients with different alanine aminotransferase levels on presentation

Cumulative HBeAg seroconversion rate (%)
Year 1Year 2Year 3Year 4Year 5
ALT, alanine aminotransferase; ULN, upper limit of normal.
All patients (n=1215)18.031.041.347.653.5
Stratified by ALT levels on presentation
    ALT <0.5×ULN (n=151)9.416.019.923.026.5
    ALT >0.5–1×ULN (n=294)11.722.632.339.547.9
    ALT >1–2×ULN (n=284)12.828.940.146.253.0
    ALT >2×ULN (n=486)28.244.958.466.672.4
        ALT >2–5×ULN (n=243)24.939.553.559.867.5
        ALT >5×ULN (n=243)31.550.663.774.778.1