Parameters of acute exacerbation in patients with and without hepatitis B e antigen (HBeAg) seroconversion
| Acute exacerbation with HBeAg seroconversion (n=297) | Acute exacerbation without HBeAg seroconversion (n=468) | p Value | |
|---|---|---|---|
| All values are median (range). | |||
| ALT, alanine aminotransferase; AFP, α fetoprotein. | |||
| Peak ALT (U/l) | 279 (75–3990) | 191 (75–3955) | <0.0001 |
| Peak bilirubin (μmol/l) | 17 (4–390) | 15 (2–868) | 0.045 |
| Peak AFP (ng/ml) | 10 (1–3958) | 7 (1–2015) | 0.001 |
| Duration of acute exacerbation (weeks) | 24 (1–236) | 17 (1–436) | 0.018 |