Table 1

Characteristics of the study cohort

Exposed to 5-aminosalicylic acid*
In the 1st trimester or 30 days before pregnancy (n=60)During pregnancy (n=88)Not exposed* (n=19 418)
*Represents 52 women exposed during the first time period, 74 during the second time period, and 16 486 different unexposed women.
Mother's age (y)
    Mean (SD) 30.1 (4.8) 30.7 (4.4) 28.7 (4.7)
    Range 21–42 21–42 13–47
Smokers (n (%)) 9 (15.0) 14 (15.9)5102 (26.3)
Parity >1 (n (%)) 30 (50.0) 53 (60.2)9191 (47.3)
Preterm birth (gestational age <37 weeks) (n (%)) 6 (10.0) 8 (9.1)1062 (5.5)
Birth weight (g)
    Mean (SD)3564 (639)3567 (579)3503 (587)
    Range1310–55501310–5550 500–6230
Low birth weight (< 2500 g) (n (%)) 3 (5.0) 4 (4.6) 844 (4.4)
Congenital malformation (n (%)) 4 (6.7) 5 (5.7) 711 (3.7)
Stillbirth (n (%)) 2 (3.3) 3 (3.4) 109 (0.6)