Transmission disequilibrium test (TDT) analyses performed in 381 inflammatory bowel disease (IBD) families. Analyses were performed for the ulcerative colitis (UC), Crohn’s disease (CD), and IBD (UC, CD, and indeterminate colitis (IC)) phenotypes where appropriate
| A allele* | Transmitted | Untransmitted | p Value |
|---|---|---|---|
| *The A allele of the G796A polymorphism corresponds to the K allele of the E266K variation observed at the protein level. | |||
| All IBD families (n=381) | |||
| IBD phenotype | 137 | 151 | 0.40 |
| CD phenotype | 102 | 106 | 0.78 |
| UC phenotype | 25 | 37 | 0.12 |
| Pure CD families (n=235) | |||
| CD phenotype | 85 | 87 | 0.87 |
| Pure UC families (n=58) | |||
| UC phenotype | 19 | 21 | 0.75 |