Recurrences overall and by stage (I, II, and III) compared with the status of BRCA1 loss of heterozygosity (LOH)
| Informative cases (%) | With LOH (%) | Without LOH (%) | p Value | |
|---|---|---|---|---|
| Overall recurrences | ||||
| Yes | 51 (23.8) | 31 (60.8) | 20 (39.2) | 0.0003 |
| No | 163 (76.2) | 53 (32.5) | 110 (67.5) | |
| Stage I | ||||
| Yes | 5 (17.2) | 5 (100) | 0 | 0.008 |
| No | 24 (82.8) | 6 (25) | 18 (7.5) | |
| Stage II | ||||
| Yes | 14 (14.6) | 10 (71.4) | 4 (28.6) | 0.01 |
| No | 82 (85.4) | 26 (31.7) | 56 (68.3) | |
| Stage III | ||||
| Yes | 32 (36) | 16 (50) | 16 (50) | 0.32 |
| No | 57 (64) | 21 (36.8) | 36 (73.2) | |