Effect of corticosteroids on the value of the maximal transport rate (Vmax) and the Michaelis affinity constant (Km) of d-glucose in the jejunum and ileum of rats undergoing intestinal resection
| Drug | Jejunum | Ileum | ||
|---|---|---|---|---|
| Vmax | Km | Vmax | Km | |
| Values are mean (SEM); n=6. | ||||
| Vmax (maximal transport rate) is given in nmol×100 mg/tissue/min. | ||||
| Km (Michaelis affinity constant) is given in mM. | ||||
| *p<0.05, budesonide, prednisone, or dexamethasone versus control; †p<0.05, prednisone or dexamethasone versus budesonide. | ||||
| Control | 3066 (217) | 39.7 (5.5) | 2726 (320) | 59.7 (11.9) |
| Budesonide | 6790 (803)* | 93.7 (16.5)* | 5091 (964) | 131.1 (34.0) |
| Prednisone | 2531 (535)† | 35.7 (15.2)† | 9354 (3313) | 239.3 (102.8) |
| Dexamethasone | 2991 (283)† | 39.3 (7.3)† | 5062 (2464) | 118.3 (80.7) |