Effect of corticosteroids on expression of mRNAs for the early response genes of rats undergoing intestinal resection
| Drug | Jejunum | Ileum | ||||
|---|---|---|---|---|---|---|
| c-myc | c-jun | c-fos | c-myc | c-jun | c-fos | |
| Values are mean (SD); n=3. | ||||||
| Ratio of treatment (glucocorticosteroids) versus control animals. | ||||||
| *p<0.05, budesonide, prednisone or dexamethasone versus control; NS, no signal. | ||||||
| Control | 1 (0) | 1 (0 | NS | 1 (0) | 1 (0) | NS |
| Budesonide | 1.08 (0.70) | 0.43 (0.02)* | NS | 0.83 (0.23) | 0.99 (0.54) | NS |
| Prednisone | 1.84 (1.83) | 0.46 (0.02)* | NS | 1.22 (0.48) | 1.42 (1.00) | NS |
| Dexamethasone | 1.03 (0.79) | 0.54 (0.11)* | NS | 1.06 (0.14) | 1.02 (0.18) | NS |