Log linear analysis of variants in British Crohn’s disease. Two locus model: allele frequencies
| Cohort | Frequencies of observed allelic combinations | |||
|---|---|---|---|---|
| Arg702 | Arg702 | 702Trp | 702Trp | |
| IBD5- | IBD5+ | IBD5- | IBD5+ | |
| Control | 56.4% | 37.9% | 3.5% | 2.2% |
| Case | 47.9% | 42.1% | 6.0% | 4.0% |
| Leu1007 | Leu1007 | 1007fsinsC | 1007fsinsC | |
| IBD5- | IBD5+ | IBD5- | IBD5+ | |
| Control | 59.1% | 39.4% | 1.5% | 0% |
| Case | 47.3% | 45.3% | 4.9% | 2.5% |
| TNF-857T | TNF-857T | TNF-857C | TNF-857C | |
| IBD5- | IBD5+ | IBD5- | IBD5+ | |
| Control | 5.5% | 1.5% | 55.0% | 38.0% |
| Case | 2.8% | 1.5% | 49.0% | 46.8% |
| Arg702 | Arg702 | 702Trp | 702Trp | |
| TNF-857T | TNF-857C | TNF-857T | TNF-857C | |
| Control | 5.9% | 88.5% | 0.7% | 4.8% |
| Case | 4.4% | 85.7% | 0.4% | 9.5% |
| Leu1007 | Leu1007 | 1007fsinsC | 1007fsinsC | |
| TNF-857T | TNF-857C | TNF-857T | TNF-857C | |
| Control | 4.3% | 87.8% | 0.7% | 7.2% |
| Case | 6.5% | 92.2% | 0.0% | 1.3% |