Log linear analysis of variants in British Crohn’s disease. Two locus model: tests of association after conditioning on potential gene-gene interactions
| Crohn’s disease association (main effects) | χ21 | p Value |
|---|---|---|
| IBD5, conditioned on | ||
| CARD15 (Arg702Trp) | 6.9 | 0.008 |
| CARD15 (Leu1007fsinsC) | 6.3 | 0.01 |
| TNF−857C | 7.1 | 0.008 |
| CARD15 (Arg702Trp), conditioned on | ||
| IBD5 | 4.5 | 0.03 |
| TNF−857C | 6.1 | 0.01 |
| CARD15 (Leu1007fsinsC), conditioned on | ||
| IBD5 | 9.0 | 0.003 |
| TNF−857C | 15.2 | <0.0001 |
| TNF−857C, conditioned on | ||
| IBD5 | 1.7 | 0.2 |
| CARD15 (Arg702Trp) | 1.4 | 0.2 |
| CARD15 (Leu1007fsinsC) | 1.5 | 0.2 |