Frequency of adverse events by treatment group (intention to treat population)
| Placebo (n=48) | 0.1% GTN (n=49) | 0.2% GTN (n=47) | 0.4% GTN (n=37) | All patients (n=181) | |
|---|---|---|---|---|---|
| χ2 test for trend, glyceryl trinitrate (GTN) versus placebo (χ2=50.5, p<0.0001). | |||||
| Adverse event | |||||
| Headache (n (%)) | 6 (12.5%) | 9 (18.3%) | 17 (36.1%) | 25 (67.5%) | 57 (31.5%) |
| Severe headache (n (%)) | 2 (4.2%) | 1 (2.0%) | 3 (6.3%) | 9 (24.3%) | 14 (7.7%) |