Table 1

Patient baseline characteristics

Patient characteristicPlacebo (n=221)Rofecoxib 50 mg (n=219)Naproxen 500 mg twice daily (n=220)
NSAIDs, non-steroidal antiinflammatory drugs; GI, gastrointestinal; PUBs, gastrointestinal perforations, ulcers, or bleeding episodes.
Female (%)828678
Mean age (y)515351
≥65 years (%)162016
% from USA222122
% White485252
History of upper GI events (PUBs) (%)101114
H pylori positive (%)616157
% with baseline gastroduodenal erosions111314
Tobacco use (%)383440
Corticosteroids (%)615659
Prior NSAID use (%)706857