Table 1

Interleukin 10 (IL-10) (−1082) polymorphism allele and genotype distribution

IBS (n=230)Controls (n=450)
*Odds ratio (OR) 1.17 (95% confidence interval 0.93–1.49); p=0.097.
†Fewer irritable bowel syndrome (IBS) patients of high producer (G/G) genotype (χ2=11.97, df=2, p=0.003), with more patients carrying A allele (A+: G/A or A/A) (χ2=8.08, OR 1.72 (1.18–2.50), p=0.004)‡.
§n= number of alleles in each group, being twice the number of individuals as two alleles are inherited.
¶n=number of individuals with specific genotype.
    Allele frequency§
        −1082*G (high)21948*43852
        −1082*A (low)2415241248
        G/G (high producer)4921†13532
        G/A (intermediate)1215316839
        A/A (low producer)602612229
        A− (G/G)4921‡13532
        A+ (A/A or G/A)1817929068