Table 3

Association testing based on the haplotype frequencies of A→G1364, A→C2607, and DEL2609

*Number of individuals.
†The relevant test statistic is T= ln(L, cases) + ln(L, controls) − ln(L, cases+controls together). Twice this value has an approximate χ2 distribution with a number of degrees of freedom (df) equal to the number of haplotypes estimated. For the above data: (−90.84) + (−97.86) − (−192.24) = 3.54; χ2=2×3.54 = 7.08 which on 7 df is associated with an empirical significance level of p=0.42.
All subjects162−192.2456.49