Table 2

Standardised incidence ratios (SIRs) for liver and biliary cancer in offspring by cancer in parents

FatherMotherParents
Parental cancerOSIR95%CIOSIR95%CIOSIR95%CI
Values in bold type indicate that 95% confidence interval (95% CI) does not include 1.00.
O, observed.
Upper aerodigestive tract19 2.20 1.32 3.45 10.370.002.1020 1.76 1.07 2.73
Stomach190.980.591.54101.050.501.94291.010.671.45
Small intestine21.860.176.8333.090.589.1652.440.775.75
Colon160.900.511.46160.850.481.38320.870.601.23
Rectum141.130.621.90141.600.872.69281.330.881.92
Liver and biliary60.990.362.1818 2.11 1.25 3.34 24 1.65 1.05 2.46
Pancreas19 2.22 1.33 3.47 70.900.361.8626 1.59 1.04 2.33
Lung321.280.871.8150.600.191.40371.110.781.53
Breast460.950.691.26460.940.691.25
Cervix151.480.822.44151.480.822.44
Endometrium151.250.692.06151.250.692.06
Ovary100.880.421.62100.880.421.62
Prostate771.150.911.44771.150.911.44
Kidney60.660.241.4514 1.89 1.03 3.18 201.220.741.88
Urinary bladder261.500.982.2061.180.432.59321.430.982.02
Melanoma10.230.001.3181.700.733.3690.990.451.89
Skin70.710.281.46101.610.772.97171.050.611.69
Nervous system30.540.101.5971.030.412.13100.810.381.49
Thyroid gland51.920.614.5351.390.443.26
Endocrine glands6 3.20 1.15 7.01 11 2.05 1.02 3.68 17 2.34 1.36 3.76
Non-Hodgkin’s lymphoma60.910.331.9840.670.181.74100.800.381.47
Myeloma40.930.242.4071.960.784.05111.400.692.51
Leukaemia50.660.211.5571.170.462.42120.880.451.55
All268 1.15 1.01 1.29 239 1.19 1.04 1.35 507 1.16 1.07 1.27