Table 2

Clinicopathological associations of E-cadherin methylation in patients with gastric cancer

E-cadherin
Clinicopathological parameterMethylated (%)Unmethylated (%)p Value
*Mean (SD).
Age (y)*65 (14)58 (13)NS
H pylori
    Present6 (67%)3 (33%)NS
    Absent5 (56%)4 (44%)
Histological subtype
    Mucinous/signet ring8 (80%)2 (20%)NS
    Tubular7(44%)9 (56%)
Regional nodal metastasis
    N01 (20%)4 (80%)0.05
    N1/N214 (67%)7 (33%)
Depth of invasion
    T10 (0%)3 (100%)0.02
    T2/T3/415 (65%)8 (35%)
Distant metastasis
    Present2 (50%)2 (50%)NS
    Absent13 (59%)9 (41%)