Prevalence of gastrointestinal diseases in two British birth cohorts
| Rate; prevalence per 10 000 (95% CI) | |||
|---|---|---|---|
| BCS70—30 years of age | NCDS—30 years of age | NCDS—42 years of age | |
| BCS70, 1970 British cohort study; NCDS, National Child Development Study; 95% CI, 95% confidence interval. | |||
| Crohn’s disease | |||
| Male | 21/5443; 38.6 (22.1, 55.1) | 15/5601; 26.8 (13.2, 40.3) | 19/5601; 33.9 (18.7, 49.2) |
| Female | 21/5768; 36.4 (20.9, 52.0) | 9/5774; 15.6 (5.4, 25.8) | 18/5774; 31.2 (16.8, 45.6) |
| Total | 42/11211; 37.5 (26.2, 48.8) | 24/11375; 21.1 (12.7, 29.5) | 37/11375; 32.5 (22.1, 43.0) |
| Ulcerative colitis | |||
| Male | 13/5443; 23.9 (10.9, 36.9) | 15/5601; 26.8 (13.2, 40.3) | 30/5601; 53.6 (34.4, 72.7) |
| Female | 21/5768; 36.4 (20.9, 52.0) | 16/5774; 27.7 (14.1, 41.3) | 37/5774; 64.1 (43.5, 84.7) |
| Total | 34/11211; 30.3 (20.1, 40.5) | 31/11375; 27.3 (17.7, 36.8) | 67/11375; 58.9 (44.8, 73.0) |
| Irritable bowel syndrome | |||
| Male | 195/5443; 358.3 (309.9, 407.6) | 91/5601; 162.5 (129.4, 195.6) | 273/5601; 487.4 (431.0, 543.8) |
| Female | 731/5768; 1267.3 (1181.5, 1353.2) | 249/5774; 431.2 (378.8, 483.7) | 686/5774; 1188.0 (1104.6, 1271.6) |
| Total | 926/11211; 826.0 (775.0, 876.9) | 340/11375; 289.9 (267.6, 330.2) | 959/11375; 843.1 (792.0, 894.1) |
| Gall stones | |||
| Males | 20/5443; 36.7 (20.7, 52.8) | 15/5601; 26.8 (13.2, 40.3) | 46/5601; 82.1 (58.5, 105.8) |
| Females | 79/5768; 137.0 (107.0, 167.0) | 74/5774; 128.2 (99.1, 157.2) | 219/5774; 379.3 (330.0, 428.6) |
| Total | 99/11211; 88.3 (71.0, 105.6) | 89/11375; 78.2 (62.0, 94.4) | 265/11375; 233.0 (205.2, 260.7) |
| Peptic ulcer disease | |||
| Male | 173/5443; 317.8 (271.2, 364.4) | 182/5601; 324.9 (278.5, 371.4) | 309/5601; 551.7 (491.9, 611.5) |
| Female | 100/5768; 173.4 (139.7, 207.1) | 78/5774; 135.1 (105.3, 164.9) | 192/5774; 332.5 (286.2, 378.8) |
| Total | 273/11211; 243.5 (214.4, 272.6) | 260/11375; 228.6 (201.1, 256.0) | 501/11375; 440.4 (402.7, 478.2) |