Table 1

Characteristics of the primary biliary cirrhosis (PBC) patients studied

PretreatmentDuring UDCA
Patient NoAge (y)Body weight (kg)Bilirubin (mg/dl) (0.3–1.2)AP (mU/ml) (30–85)γGT (mU/ml) (5–50)ALT (mU/ml) (5–50)Histology (stage)Bilirubin (mg/dl)AP (mU/ml)γGT (mU/ml)ALT (mU/ml)
†Patients were studied twice with the 75SeHCAT test: pretreatment and during ursodeoxycholic acid (UDCA) administration.
Normal ranges for alkaline phosphatase (AP), γ-glutamyl transpeptidase (γGT), and alanine aminotransferase (ALT) are shown in parentheses.
***p<0.001 compared with pretreatment.
        1†64750.71337360II0.6922530
        2†55470.61039232II0.6834630
        3†63470.623641960II–III0.611015229
        4†23820.4591400360I–II0.4414303250
        5†52580.4320120104I–II0.82408080
        6†50550.450020280I1.03408255
        7†46611.044818092I–II0.820810248
        8†70560.518231150II–III0.69510536
        9†49771.4750836182III–IV1.418019042
    10†40600.651226048I0.81388840
    11†50500.6694193123III0.52728286
        1257581.0652297113I–II1.065731750
        1348430.574822681II0.623630957
        1465501.0282310125IV0.813312450
Mean52590.74392801080.8228***143***63***
        SD12120.3230191830.31589856