Genotype frequencies | ||||
---|---|---|---|---|
H2/H2 (%) | H2/non-H2 (%) | Non-H2/non-H2 (%) | H2 haplotype frequency (%) | |
p values in bold are significant (p<0.05) after Bonferroni correction factor of 24 (3 phenotypes×8 haplotypes tested for association). | ||||
RR, relative risk. | ||||
Perianal (n=144) | 37 (25.7) | 76 (52.8) | 31 (21.5) | 52.1 |
No perianal (n=186) | 39 (21.0) | 81 (43.5) | 66 (35.5) | 42.2 |
Controls (n=870) | 128 (14.7) | 421 (48.4) | 321 (36.9) | 38.9 |
Significance p/RR (95% CI) | ||||
Perianal v no perianal | 0.02/2.0 (1.1–3.7) | 0.01/2.0 (1.2–3.4) | — | 0.01/1.5 (1.1–2.0) |
Perianal v controls | <0.0001/3.0 (1.8–5.0) | 0.005/1.9 (1.2–2.9) | — | <0.0001/1.7 (1.3–2.2) |