Effects of ghrelin administered intraperitoneally (3 nmol/mouse every 12 hours for five days) on calorie intake, epididymal fat mass, gastrocnemius muscle, and blood glucose, insulin, cholesterol, triglycerides, and free fatty acid concentrations in lean mice under a high fat diet
| LF, saline | HF, saline | HF, ghrelin | |
|---|---|---|---|
| Results are expressed as mean (SEM). | |||
| LF and HF indicate a standard diet and a high fat diet, respectively. | |||
| *p<0.05, **p<0.01 between saline treated mice fed a standard diet and ghrelin treated mice fed a high fat diet. | |||
| †p<0.05 between saline treated mice fed a high fat diet and ghrelin treated mice fed a high fat diet. | |||
| Calorie intake (kcal/day) | 18.83 (1.055) | 23.22 (1.329) | 25.94 (2.562)* |
| Fat pad mass(g) | 0.533 (0.049) | 0.797 (0.095) | 1.202 (0.175)**† |
| Skeletal musde (g) | 0.337 (0.016) | 0.353 (0.010) | 0.340 (0.005) |
| Glucose (mmol/l) | 7.899 (0.476) | 8.393 (0.825) | 8.909 (0.498) |
| Insulin (pmol/l) | 135.0 (20.10) | 177.5 (13.05) | 378.0 (141.8)* |
| Cholesterol (mmol/l) | 3.742 (0.337) | 5.568 (0.497) | 5.813 (0.509)** |
| Triglycerides (mmol/l) | 0.347 (0.032) | 0.305 (0.039) | 0.371 (0.090) |
| Free fatty acids (meq/l) | 1.467 (0.050) | 1.623 (0.100) | 1.636 (0.047) |