Characteristics of the first five study subjects
| Mr Y | Mrs X | Mr A | Mr Q | Mr R | |
|---|---|---|---|---|---|
| PPI, proton pump inhibitors; PmHx, past medical history. | |||||
| Cannabis use age of onset (y) | 19 | 17 | 16 | 17 | 12 |
| Cyclical vomiting (y) | 22 | 20 | 22 | 34 | 17 |
| Illness duration (y) | 15mths | 9 | 12 | 3 | 4 |
| Cannabis cessation | Well for 9mths//2y | Well for 4y//2y | Well for 18mths | Well for 18mths | Did not cease |
| Cannabis resumption | Vomiting at 8 weeks | Vomiting at 3mths | Nil | NIL | Ongoing illness |
| Compulsive bathing | Multiple hot showers | Multiple hot baths | Multiple hot baths | Multiple hot showers | Multiple hot showers |
| Prodromal illness | Yes (6mths) | No | Yes (1 y) | No | No |
| Cannabis dose (daily dose) | Heavy (5–10 cones) | Light (1–5 cones) | Heavy (5–10 cones) | Heavy (5–10 cones) | Heavy (5–10 cones) |
| Noted dose response (increased cannabis use) | Yes (increased for back pain) | – | – | Yes (increased for anxiety) | – |
| Hospital admissions | Multiple | Multiple | Multiple | Multiple | Multiple |
| IVI fluids | Required | Required | Required | Required | Required |
| Cyclical presentation (months) | 1–2 | 2–3 | 2–3 | 1–2 | 3–4 |
| Pyrexia (noted in ward notes) | Not noted | Noted | Not noted | Not noted | Noted |
| Thirst | +++ | +++ | +++ | +++ | +++ |
| Weight loss (kg) (during illness) | 10 | 10 | 10 | Nil | 10 |
| Weight gain (kg) (on cessation) | 10 (at 3mths) | 10 (at 3mths) | 10 (at 6mths) | Nil | Nil |
| Other illicit drugs used | None | None | None | None | None |
| Alcohol abuse | None | None | None | None | Moderate |
| Medications | PPI | PPI | PPI | PPI | PPI |
| PmHx hyperemesis gravidarum | – | Severe | – | – | – |
| Psychiatric Dx | None | None | None | None | None |