Sensitivity, specificity, and predictive values for the C/C-13910 genotype defining low lactase activity in a series of 329 children. Lactase activity below 10 U/g protein was used as a cut off point for low enzyme activity
Age group | |||
---|---|---|---|
⩽5 years (n = 109) | 6–11 years (n = 142) | ⩾12 years (n = 78) | |
Sensitivity | 80.0% | 94.6% | 93.3% |
Specificity | 65.4% | 81.9% | 100.0% |
Predictive value positive | 10.0% | 64.8% | 100.0% |
Predictive value negative | 98.6% | 97.7% | 98.4% |