Table 1

 Characteristics of Crohn’s disease patients with the NOD2 wild-type genotype or NOD2 mutations, and controls. In the case of non-inflamed controls, colonoscopy was performed for polyps, anaemia, post surgical follow up, or tumour

Crohn’s disease wild-typeCrohn’s disease NOD2 mutationControls
n4424 (SNP13: 15, SNP8: 4, SNP12: 4)12
Age (y) (median (range))32 (17–67)41 (16–70)30 (20–65)
Disease duration (y) (median (range))7 (0–36)10 (0–41)
Ileal involvement58%88%
Three most common treatments
    Steroids42%44%
    5-ASA57%66%
    Azathioprine28%22%