Other histopathological abnormalities in 115 patients with chronic idiopathic intestinal pseudo-obstruction (CIIP) in comparison with α-actin deficiency
| ICCs, interstitial cells of Cajal. | |
| *From n = 13: recent Swedish series only. Less marked alterations were also noted in other patients, including focal decreases in ICC number around ganglia and hyperplasia/hypertrophy. | |
| α-Actin deficiency | 28 (24%) |
| Neuropathic | |
| Degenerative neuropathy | 20 (17%) |
| Inflammatory plexitis | 20 (17%) |
| Lymphocytic ganglionitis | 13 (11%) |
| Myopathic | |
| Degenerative leiomyopathy | 16 (14%) |
| Vacuolar myopathy | 7 (6%) |
| Hollow visceral myopathy | 4 (3%) |
| Inclusion body myopathy | 4 (3%) |
| Inflammatory leiomyositis | 1 (1%) |
| Interstitial cell abnormalities | |
| Decreased number ICCs | 2 (15%)* |