Demographic data of seven subjects who harboured a determinant mutants in the 1999 survey
| Case No | Age (y) | Sex | HBsAg/anti-HBs | HBeAg/anti-HBe | HBIG/Vac | Maternal HBsAg | Mutant | |
|---|---|---|---|---|---|---|---|---|
| HBsAg, hepatitis B surface antigen; anti-HBs, antibody to hepatitis B surface antigen; HBeAg, hepatitis B e antigen; anti-HBe, antibody to hepatitis B e antigen; HBIG/Vac, received HBIG injection at birth/doses of HB vaccine received during infancy; Maternal HBsAg, maternal HBsAg status at the patient’s birth; NA, not available. | ||||||||
| Family members were studied for hepatitis B virus (HBV) markers and HBV-DNA in serum after the 1999 survey and revealed the following: | ||||||||
| Case 99-3: father HBsAg(+), S132Y; mother HBsAg(+), wild-type; younger sister HBsAg(−) HBV-DNA(−). | ||||||||
| Case 99-2: serum of her mother was resampled in 2001 and was found to be HBsAg(−) and HBV-DNA(−). | ||||||||
| Case 99-1, mother HBsAg(+), HBV-DNA(+), wild-type. | ||||||||
| Children | 99-1 | 0.2 | M | −/− | −/− | +/1 | + | T131I |
| 99-2 | 9.5 | F | +/− | +/− | +/3 | + | G145R | |
| 99-3 | 9.5 | M | +/− | +/− | +/4 | + | G145R | |
| Adolescents | 99-4 | 15.1 | M | +/− | +/− | −/0 | + | M133L |
| 99-5 | 15.9 | M | +/− | +/− | −/0 | NA | T123A | |
| 99-6 | 17.3 | F | +/− | +/− | −/0 | NA | P127T | |
| 99-7 | 17.2 | M | −/+ | −/+ | −/0 | NA | N146I | |