Table 4

Reactivity of purified IgG obtained from pooled sera of ulcerative colitis and Crohn’s disease patients to different bacterial species isolated from the rectal mucosa*

Bacterial isolatesUC (n = 27)CD (n = 24)
*Results are expressed as a percentage increase/decrease over healthy donor IgG responses (n = 14). Concentrations of IgG and IgG subclasses were equalised between the three experimental groups before immunofluorescence staining.
CD, Crohn’s disease; UC, ulcerative colitis.
Total IgG
    Peptostreptococcus anaerobius13829
    Bacteroides fragilis104−5
    Enterococcus faecalis111−23
    Clostridium clostridioforme142−6
    Bifidobacterium adolescentis38−30
    Bif angulatum1013
    Lactobacillus paracasei14333
    Escherichia coli20860
IgG1
    Peptostreptococcus anaerobius1147
    Bacteroides fragilis47−37
    Enterococcus faecalis100−25
    Clostridium clostridioforme73−21
    Bifidobacterium adolescentis50−37
    Bif angulatum71−37
    Lactobacillus paracasei93−21
    Escherichia coli123−6
IgG2
    Peptostreptococcus anaerobius72275
    Bacteroides fragilis−21116
    Enterococcus faecalis24135
    Clostridium clostridioforme−1944
    Bifidobacterium adolescentis−8860
    Bif angulatum−12110
    Lactobacillus paracasei−2920
    Escherichia coli−1464