Table 1

Baseline demographics of the two study groups

No PPHTNPPHTN
Values are mean (SEM) or number (%).
PPHTN, portopulmonary hypertension; ALT, alanine aminotransferase; ASP, aspartate aminotransferase; INR, international normalised ratio; HCV, hepatitis C viral infection; HBV, hepatitis B viral infection.
n 52 10
Sex (M:F)46:67:3
Mean age (y) 54.5 (1.4) 52.7 (3.1)
ALT (U/l) (normal <39) 28 (4) 25 (5)
AST (U/l) (normal <35) 55 (6) 52 (11)
Bilirubin (μmol/l) (normal <16) 32 (3) 36 (5)
Albumin (g/l) (normal 38–50) 32 (1) 34 (2)
INR (normal 0.8–1.2) 1.46 (0.03) 1.40 (0.10)
Creatinine (μmol/l) (normal <110) 99 (5)108 (14)
Varices 52 (100%) 10 (100%)
Mean Child-Pugh score 9.7 (0.2) 9.3 (0.5)
Child-Pugh class B/C 39 (75%)/13 (25%) 7 (70%)/3 (30%)
Grade of ascites 3 3
Aetiology
    Alcohol 33 4
    Alcohol+HCV 5 4
    HCV 4
    Alcohol + HBV 2
    HBV 4
    Cryptogenic 2 1
    Sarcoidosis 1
    Autoimmune hepatitis 1
    α1-Antitrypsin deficiency 1