Summary statistics for reporting of colorectal cancer
| Group | Relative group | No of cases reported at interview | No of cases found by record linkage | Sensitivity (95% CI) | Specificity (95% CI) | Positive predictive value (95% CI) | Negative predictive value (95% CI) |
|---|---|---|---|---|---|---|---|
| Sensitivity, the proportion of colorectal cancer cases identified by record linkage that were reported at interview; Specificity, the proportion of relatives confirmed by record linkage to be unaffected that were reported to be colorectal cancer free at interview; Positive predictive value, the proportion of reported colorectal cancer cases that were confirmed by record linkage; Negative predictive value, the proportion of individuals reported to be free of colorectal cancer at interview that were confirmed as unaffected by record linkage. | |||||||
| FDR, first degree relatives; SDR, second degree relatives; 95% CI, 95% confidence interval. | |||||||
| Cases | FDR (n = 1322) | 43 | 53 | 0.566 (0.433, 0.690) | 0.990 (0.983, 0.994) | 0.698 (0.549, 0.814) | 0.982 (0.973, 0.988) |
| Cases | SDR (n = 1968) | 21 | 48 | 0.271 (0.166, 0.410) | 0.996 (0.992, 0.998) | 0.619 (0.409, 0.792) | 0.982 (0.975, 0.987) |
| Controls | FDR (n = 1037) | 14 | 17 | 0.529 (0.310, 0.738) | 0.995 (0.989, 0.998) | 0.643 (0.388, 0.837) | 0.992 (0.985, 0.996) |
| Controls | SDR (n = 1310) | 16 | 30 | 0.333 (0.192, 0.512) | 0.995 (0.991, 0.995) | 0.667 (0.417, 0.848) | 0.985 (0.976, 0.990) |