Disease activity index (Schroeder and colleagues14)
| Activity | Index No |
|---|---|
| *Healthy is defined as the typical number of bowel movements per day during remission. | |
| †The investigator’s global assessment is reflective of the patient’s symptoms, the findings of sigmoidoscopy and physical examination, laboratory studies, and the patient’s overall status. | |
| Stool frequency | |
| Healthy* | 0 |
| 1–2 stools per day >healthy | 1 |
| 3–4 stools per day >healthy | 2 |
| >4 stools per day >healthy | 3 |
| Rectal bleeding | |
| None | 0 |
| Streaks of blood with stool less than half the time | 1 |
| Obvious blood with stool most of the time | 2 |
| Blood alone passed | 3 |
| Endoscopic appearance | |
| Normal or inactive disease | 0 |
| Mild (erythema, decreased vascular pattern, mild friability) | 1 |
| Moderate (marked erythema, absent vascular pattern, friability, erosions) | 2 |
| Severe (spontaneous bleeding, ulceration) | 3 |
| Investigator’s global assessment† | |
| Healthy/remission | 0 |
| Mild | 1 |
| Moderate | 2 |
| Severe | 3 |