Table 1

Established factors associated with more advanced fibrosis in chronic hepatitis C virus (HCV) infection

HIV, human immunodeficiency virus; HBV, hepatitis B virus.

  • Male sex

  • Duration of infection

  • Acquisition of infection at >40 y

  • Long term excessive alcohol consumption

  • Long term immunosuppression (HIV, organ transplantation)

  • HBV coinfection

  • Non response to antiviral therapy