Tumour incidences and causes of death in the different groups of study animals
| Group | No of rats | Treatment | Causes of death (No of animals) |
|---|---|---|---|
| MNNG, N-methyl-N′-nitro-N-nitrosoguanidine. | |||
| A | 5 | Control | |
| B | 16 | MNNG alone | Gastric cancer (6) |
| C | 16 | MNNG+indomethacin (3 mg/kg/day) | Gastric cancer (2), small bowel cancer (3), unknown (1) |
| D | 17 | MNNG+celecoxib (5 mg/kg/day) | Gastric cancer (5) |
| E | 16 | MNNG+celecoxib (10 mg/kg/day) | Small bowel cancer (5), lung cancer (1) |
| F | 16 | MNNG+celecoxib (20 mg/kg/day) | Gastric cancer (1), intestinal haemorrhage (2) |