Proposed programme for surveillance and treatment of duodenal adenomatosis
| *Including multiple random biopsies from mucosal folds in patients without visible polyps. | |
| †Including multiple biopsies from polyps. | |
| Spigelman stage 0 | Endoscopy* at intervals of 5 y |
| Spigelman stage I | Endoscopy† at intervals of 5 y |
| Spigelman stage II | Endoscopy† at intervals of 3 y |
| Spigelman stage III | Endoscopy† at intervals of 1–2 y |
| Spigelman stage IV | Endoscopic ultrasonography |
| Consider pancreas sparing or pylorus sparing duodenectomy | |