Table 1

Diagnostic value of volatile organic compounds (VOCs) from stool samples from patients with infectious diarrhoea

MarkerPresent in specific diseasePresent in remainderχ2p ValueSensitivity (%)Specificity (%)PPV (%)NPV (%)
The strength of association is shown using the χ2 test with Yates’ correction, sensitivity and specificity, and positive predictive (PPV) and negative predictive (NPV) values.
3MI, 3-methylindole; 2FC, 2-furancarboxaldehyde; 5M2FC, 5-methyl-2-furancarboxaldehyde; EDD, ethyl dodecanoate.
C difficile (i) 3MI negative1/625/383.30.0683652896
C difficile (ii) 2FC positive6/68/3811.50.00071008040100
C difficile (iii) 3MI negative, 2FC positive5/61/3822.22.6 E−683978397
C difficile (iv) 5M2FC positive5/61/3822.22.6 E−683978397
C difficile (v) 3MI negative, 5M2FC positive4/60/3820.46.3 E−66710010095
Campylobacter No terpenes/hydrocarbons5/53/3919.61 E−51009263100
RotavirusEDD positive5/51/3927.91.3 E−71009783100
Non-rota enteritisAmmonia positive, EDD negative11/191/2515.48.6 E−563969277