Table 1

Demographic, biochemical, metabolic, and histological parameters of patients in the lifestyle intervention programme

ParameterTotal group (n = 35)HCV (n = 21)Non-HCV (n = 14)p Value*Reference range
Values are mean (SD) or number.
*Independent t test HCV versus non-HCV groups; †Fisher’s exact test.
HCV, hepatitis C virus; NASH, non-alcoholic steatohepatitis; BMI, body mass index; HOMA, homeostasis model of assessment; ALT, alanine aminotransferase; DM, diabetes mellitus.
Age (y)43.8 (9.6)43.4 (9.8)44.4 (9.7)0.77
Sex M/F† (% male)21/14 (60)11/10 (52)10/4 (71)0.26
Type 2 DM (n)312
BMI (kg/m2)30.5 (5.9)29.3 (4.5)32.3 (7.3)0.14
Waist (cm)100 (12)99 (11)103 (14)0.26
ALT (U/l)113 (78)138 (85)76 (49)0.02<35 U/l
Cholesterol (mmol/l)4.3 (1.3)3.7 (1.2)5.3 (0.8)<0.0001<5.5 mmol/l
Triglyceride (mmol/l)1.4 (1.0)1.2 (0.8)1.8 (1.2)0.12<2.0 mmol/l
Insulin (mU/l)15 (7)14 (7)15 (7)0.86<20 mU/l
Glucose (mmol/l)5.7 (1.4)5.3 (1.3)6.1 (1.4)0.09<6.0 mmol/l
HOMA3.7 (2.6)3.7 (3.0)3.7 (1.8)0.99<1.64
Steatosis (median)2220.15
NASH† (n)8260.04
Fibrosis (median) (Knodell score 0−6)2310.09