Factors associated with long term weight loss and weight maintenance or regain after a lifestyle intervention
| Factors at onset or during lifestyle intervention | Maintainers (n = 21) | Regainers (n = 10) | p Value |
|---|---|---|---|
| *χ2. | |||
| Values are mean (SD) or number. | |||
| HCV, hepatitis C virus; BMI, body mass index; HOMA, homeostasis model of assessment; ALT, alanine aminotransferase. | |||
| Age (y) | 43.1 (8.0) | 41.5 (10.3) | 0.64 |
| Sex (M/F)* (% male) | 14/7 (67) | 7/3 (70) | 0.85 |
| Initial BMI (kg/m2) | 30.6 (6.6) | 30.6 (4.4) | 0.98 |
| Weight loss t = 0 to t = 3 (%) | 5.9 (3.3) | 6.8 (3.2) | 0.47 |
| Waist loss t = 0 to t = 3 (%) | 7.5 (4.0) | 11.6 (4.9) | 0.02 |
| ALT t = 0 (U/l) | 107 (75) | 115 (89) | 0.80 |
| Insulin t = 0 (mU/l) | 16 (6) | 11 (5) | 0.03 |
| HOMA t = 0 | 4.1 (1.7) | 2.5 (1.3) | 0.02 |
| Non-HCV/HCV (%HCV) | 10/11 (52) | 3/7 (70) | 0.35 |
| Amount exercise t = 0 to t = 3 (min/week) | 185 (195) | 245 (82) | 0.04 |
| Amount of exercise t = 3 to t = 15 (min/week) | 150 (160) | 50 (55) | 0.02 |