Table 3

 Toll-like receptor 4 (TLR4) genotypes in the study populations

CD cohort 1 (n = 334)*CD cohort 2 (n = 113)**UC (n = 163)***Controls (n = 139)
CD, Crohn’s disease; UC, ulcerative colitis.
All p values are compared with controls: *p = 0.012, **p = 0.017, ***p = 0.08.
Genotype
    Wild-type265 (79.3%)88 (77.9%)133 (81.6%)126 (90.6%)
    Heterozygous65 (19.5%)24 (21.2%)28 (17.2%)12 (8.6%)
    Homozygous mutant4 (1.2%)1 (0.9%)2 (1.2%)1 (0.8%)
Allele frequencies
    Minor allele10.9%11.5%9.8%5.0%