Relative risks (expressed as odds ratios) for the Toll-like receptor 4 (TLR4) and NOD2 genotypes
| Wild-type | Heterozygous | Homozygous mutant | |
|---|---|---|---|
| CD, Crohn’s disease; OR, odds ratio; 95% CI, 95% confidence interval. | |||
| For TLR4 Asp299Gly, one CD patient and one control could not be genotyped. | |||
| NOD2 mutations | |||
| CD | 251 | 163 | 34 |
| Controls | 109 | 28 | 3 |
| OR (95% CI) | 1 | 2.528 (1.562–4.11) | 4.199 (1.41–20.513) |
| TLR4 Asp299Gly | |||
| CD | 353 | 89 | 5 |
| Controls | 126 | 12 | 1 |
| OR (95% CI) | 1 | 2.652 (1.356–5.274) | 1.780 (0.201–40.619) |