Table 2

Fatal adverse events

DiagnosisAge (y)SexConcomitant medicationNo of infusionsTime between first infusion and adverse eventCause of DeathSpecific comments
CD, Crohn’s disease; UC, ulcerative colitis; NK, natural killer; GCS, glucocorticosteroids; TNF-α, tumour necrosis factor α.
CD25MAzathioprine+GCS11 yNK cell lymphomaTissue staining positive for TNF-α
CD79MGCS11 yB cell lymphoma
UC57MGCS16 weeksPneumocystis carinii. Progressive pulmonary fibrosis and respiratory failure
UC73MGCS12 weeksPost-op pulmonary embolism
UC67MGCS12 weeksPostop septicaemia and respiratory failure
CD75MRectal GCS3 (0, 2, 6 weeks)6 weeksPurulent bronchitis with recurrent septicaemia