Table 1

 Percentage of mice with the appearance of bloody faeces, rectal prolapse, or cachexia (evidenced by progressive weight loss (>30% loss compared with initial body weight) and signs of muscle wasting). Colonic neoplasms were induced by 1,2-dimethylhydrazine and mice then underwent a treatment free period before daily treatment with native glucagon-like peptide 2 (GLP-2), Gly2-GLP-2, or phosphate buffered saline (controls)

ControlsGLP-2Gly2-GLP-2
2 month treatment free interval (2MO)
    10 days of treatment
        Bloody faeces101111
        Rectal prolapse403937
        Cachexia060
    1 month of treatment
        Bloody faeces000
        Rectal prolapse211526
        Cachexia004
3 month treatment free interval (3MO)
    1 month of treatment
        Bloody faeces16011
        Rectal prolapse401928
        Cachexia7733