Table 3

Kaplan-Meier estimates of the proportion of initially asymptomatic patients developing symptoms of liver disease during the first 10 years of follow up

SymptomsProportion of patients developing symptoms (%)
Time since diagnosis
1 year5 years10 years
Itch15.530.846.5
Fatigue13.129.145.8
Hypochondrial pain4.08.114.4
Bone pain3.77.815.4
Ascites1.78.116.7
Bleeding varices1.03.49.2
Hepatic encephalopathy1.33.78.7
Jaundice2.89.017.0
Any symptom of PBC26.450.771.3
Liver failure3.012.223.6