Relationship between the tumour necrosis factor (TNF) and solute carrier family 11 member 1 (SLC11A1) polymorphisms and liver fibrosis
| Polymorphisms | Fibrosis | p Value | |
|---|---|---|---|
| F0–F2 | F3–F4 | ||
| *Odds ratio 8.85 (95% confidence interval 1.9–55.2); pc = 0.002. | |||
| †Three patients bearing genotype 2/1 showed F0–F2 fibrosis. | |||
| TNF −238 A/G | 17 | 14 | |
| TNF −238 G/G | 143 | 68 | 0.303 |
| TNF −308 A/G | 45 | 20 | |
| TNF −308 G/G | 115 | 62 | 0.223 |
| Genotype 2/2 | 29† | 2 | |
| Genotype 3/3 or 3/others | 131 | 80 | 0.0005* |