Biochemical, histological, and virological features divided with respect to the solute carrier family 11 member 1 (SLC11A1) polymorphisms
| SLC11A1 genotype | p Value | ||
|---|---|---|---|
| 2/2 | 3/3 or 3/other | ||
| HCV, hepatitis C virus; AST, aspartate aminotransferase; ALT, alanine aminotransferase; AP, alkaline phosphatase; GGT, gamma glutamyl transpeptidase. | |||
| Infection duration (y) | 15.2 (8.8) | 16.7 (9.8) | NS |
| Alcohol | |||
| Yes | 7 | 58 | NS |
| No | 21 | 153 | |
| Body mass index (kg/m2) | 26.1 (5.3) | 27.2 (5.7) | NS |
| AST (U/l) | 74 (53) | 69 (53) | NS |
| ALT (U/l) | 110 (86) | 124 (102) | NS |
| AP (U/l) | 175 (56) | 182 (79) | NS |
| GGT (U/l) | 57 (41) | 46 (43) | NS |
| Ferritin (ng/ml) | 150 (125) | 148 (145) | NS |
| HCV viral load (Th IU/ml) | 336 (421) | 1290 (1345) | 0.012 |
| Portal inflammation | 1.9 (1.1) | 2.5 (1.0) | 0.031 |
| Lobular inflammation | 1.8 (0.8) | 1.8 (0.9) | NS |
| Perl’s stain (+) | 7 | 59 | NS |
| Perl’s stain (−) | 21 | 134 | |
| Steatosis (yes) | 8 | 87 | NS |
| Steatosis (no) | 20 | 106 | |