Table 4

Biochemical, histological, and virological features divided with respect to the solute carrier family 11 member 1 (SLC11A1) polymorphisms

SLC11A1 genotypep Value
2/23/3 or 3/other
HCV, hepatitis C virus; AST, aspartate aminotransferase; ALT, alanine aminotransferase; AP, alkaline phosphatase; GGT, gamma glutamyl transpeptidase.
Infection duration (y)15.2 (8.8)16.7 (9.8)NS
Body mass index (kg/m2)26.1 (5.3)27.2 (5.7)NS
AST (U/l)74 (53)69 (53)NS
ALT (U/l)110 (86)124 (102)NS
AP (U/l)175 (56)182 (79)NS
GGT (U/l)57 (41)46 (43)NS
Ferritin (ng/ml)150 (125)148 (145)NS
HCV viral load (Th IU/ml)336 (421)1290 (1345)0.012
Portal inflammation1.9 (1.1)2.5 (1.0)0.031
Lobular inflammation1.8 (0.8)1.8 (0.9)NS
Perl’s stain (+)759NS
Perl’s stain (−)21134
Steatosis (yes)887NS
Steatosis (no)20106