Univariate analysis of factors influencing severe (2 points or more) fibrosis progression
| Demographic factor | Progressed (n = 23) | No progression (n = 187) | *p Value |
|---|---|---|---|
| Risk factors for fibrosis progression in patients with hepatitis C with severe progressive (2 points or more) or non-progressive liver fibrosis (regression of fibrosis, no progression of fibrosis, and 1 point progression of fibrosis), between biopsies 1 and 2. | |||
| No data available on risk factors for 10 patients, hepatitis B virus markers for 11 patients, aminotransferase levels for one patient, and hepatitis C virus genotypes for 58 patients. | |||
| *p values for univariate analysis. | |||
| †Median values. | |||
| **χ2 for linear trend. | |||
| Sex | |||
| Male | 13 | 109 | |
| Female | 10 | 78 | NS |
| Alcohol (units/week)† | 4.5 | 5.0 | NS |
| Age at index biopsy (y)† | 45.6 | 36.2 | 0.001 |
| Age at infection (y)† | 27.4 | 18.7 | 0.05 |
| Duration of infection (y)† | 24.7 | 18.7 | 0.04 |
| Route of transmission | |||
| Injecting drug use | 13 | 100 | |
| Other | 10 | 77 | NS |