Some recurrent diseases after transplantation
| Recurrence Rate at 5 y | Effect on graft* | Treatment | |
|---|---|---|---|
| *−, no effect on graft survival; +/−, rarely affects graft survival; +, occasionally affects graft survival; +++, usually reduces graft survival. | |||
| †Transplantation does not cure haemochromatosis. | |||
| PBC, primary biliary cirrhosis; PSC, primary sclerosing cholangitis; AIH, autoimmune hepatitis; HCC, hepatocellular carcinoma; CCA, choangiocarcinoma; UDCA, ursodeoxycholic acid; IFN, interferon; Riba, ribavirin. | |||
| Autoimmune | |||
| PBC | 25% | +/− | ?UDCA |
| PSC | 50% | ++ | Uncertain |
| AIH | 10% | + | Steroids |
| Viral | |||
| Hepatitis A | N/A | − | Nil |
| Hepatitis B | Variable | + | Lamuvidine |
| Hepatitis C | 85% | ++ | IFN+Riba |
| Cancer | |||
| HCC | Variable | Variable | Nil |
| CCA | High | +++ | Nil |
| Metabolic | |||
| Haemochromatosis | High† | +/− | Venesection |