Variable | Total HH group (n = 33) | HH untreated (n = 21) | HH treated* (n = 12) | ID (n = 9) | Controls (n = 10) |
---|---|---|---|---|---|
Values are mean (SD). | |||||
HH, hereditary haemochromatosis; HH untreated, patients who had not yet undergone phlebotomy therapy; HH treated, patients who were iron depleted; ID, iron deficiency. | |||||
*Mean transferrin saturation (TS) and serum ferritin (SF) for this group prior to treatment were 81% (9) and 1011 μg/l (542), respectively. Results for SF were subsequently transformed logarithmically for statistical evaluation. | |||||
Normal laboratory values: SF 20–330 μg/l; TS 25–56%; and haemoglobin (Hb) 12.0–18.0 g/dl. | |||||
No of patients (M/F) | 29/4 | 20/1 | 9/3 | 1/8 | 5/5 |
Age at diagnosis (y) | 48 (12) | 51 (11) | 44 (13) | 52 (10) | 43 (17) |
SF (μg/l) | 1532 (1318) n = 32 | 1804 (1523) | 114 (90) | 7.7 (5) | 94 (85) |
TS (%) | 79 (14) n = 29 | 77 (17) n = 18 | 66 (23) | 20 (13) | 31 (10) |
Hb (g/dl) | 15 (1.1) n = 32 | 15 (1.0) | 14 (1.0) | 10.6 (2) | 14 (1.7) |